CT-Bone®: real bone from the 3D Printer


Patients requiring skeletal augmentation, for example those with facial asymmetry resulting from either trauma or congenital defects, would be helped best with a bony implant made to match their anatomy. Typical bone augmentation implants are made from alloplastic materials (like PEEK or titanium) or the patient’s own bone is cut and repositioned. CT-Bone® is a bone-like customized implant that can be 3D printed and is converted to real bone by the patient.

3D printed CT-Bone implant for mandible augmentation

3D printed CT-Bone implant for mandible augmentation

3D printed CT-Bone implant for zygoma augmentation

3D printed CT-Bone implant for zygoma augmentation

After taking a CT-scan of the patient, a patient-specific implant is designed by our biomedical engineers in collaboration with the surgeon. This design perfectly fits on the anatomy of the patient, ensuring good bone-to-implant contact and facilitating bony ingrowth. The design is 3D printed in calcium phosphate, the main constituent of natural bone. The 3D printing process has a very high accuracy, resulting in implants that fit perfectly onto the bone of the patient, as designed. Even very complex shapes and designs can be 3D printed; for example 3D printing enables the production of implants with engineered (controlled) porosity, similar to natural bone. When implanted, CT-Bone® unifies with the patient’s own bone in the next months.

ct-bone flow

From CT-scan to 3D model to patient-specific implant design

Unlike other 3D printed ceramics (like Hydroxyapatite or Beta-TCP), CT-Bone® does not require a thermal process (sintering) to increase mechanical strength and therefore also displays better bony fusion (sintering increases crystallinity which adversely affects biodegradability). Sintering also causes shrinkage of ceramics which results in a non-optimal fit. Since CT-Bone® does not require sintering it displays better bony fusion and is dimensionally stable, so it keeps a perfect fit.

Other manufacturing methods typically produce random porosity, whereas the process of 3D printing allows complex shapes and 100% interconnected porosity.

CT-Bone® is brought to you by Xilloc in collaboration with Next21 (Tokyo, Japan) and will be available soon.


Due to overwhelming interest in CT-Bone®, we are unfortunately unable to answer everybody personally. However if you contact us we will add you to our mailing list and you will receive email updates about the availability of CT-Bone®.

Contact us for more information.


A pre-clinical study clearly shows the difference between an implant from Hydroxyapatite and an implant from CT-Bone®. The CT-Bone® implant really fuses with the original bone. Clinical studies confirm excellent bony fusion (results available upon request).

     Hydroxyapatite                                                                 CT-Bone®
Post-op HA vs CT-Bone postop
4 weeks post-op HA vs CT-Bone postop 4w
24 weeks post-op HA vs CT-Bone postop 24w

Further histological investigations showed that in the hydroxyapatite, bone-like tissue was only found in some micropores close to the surface. In CT-Bone®, large bone-like tissues penetrated into the macropores, containing activated osteoclasts, fibroblasts and even blood vessels. In addition, bone marrow formation was observed containing erythroblasts and megakaryocytes.

CT-Bone® is biodegradable by the patient’s osteoclasts and after 3 months CT-Bone® will be fused with the patient’s bone and will remodel in the osteo-cycle. CT-Bone® does not loose shape/volume over time and therefore should not be confused with a bioresorbable material that will be resorbed over time.